Identifying homologous recombination deficiency in breast cancer: genomic instability score distributions differ among breast cancer subtypes

ConclusionsThis study demonstrated that the GIS thresholds used for ovarian cancer may also be appropriate for TNBC, but not ER  + BC. GIS thresholds in TNBC were validated using clinical response data to platinum therapy.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research