Impact of gender and mutational differences in hormone receptor expressing non-small cell lung cancer

CONCLUSIONS: Women were more likely to have HR+ NSCLC than men and EGFR and KRAS mutations occurred more commonly in HR+ NSCLC. Additional studies with more strict inclusion criteria for HR+ are warranted to see if there is benefit to targeting HR in these subgroups.PMID:37700839 | PMC:PMC10494442 | DOI:10.3389/fonc.2023.1215524

Source: Ann Oncol - September 13, 2023 Category: Cancer & Oncology Authors: Robert Hsu Denaly Chen Bing Xia Rebecca Feldman Wendy Cozen Luis E Raez Hossein Borghaei Chul Kim Misako Nagasaka Hirva Mamdani Ari M Vanderwalde Gilberto Lopes Mark A Socinski Antoinette J Wozniak Alexander I Spira Stephen V Liu Jorge J Nieva Source Type: research