Elevated circulating TLR4+ monocytes in patients with liver fluke Opisthorchis viverrini is associated with advanced periductal fibrosis

Conclusions: We propose that excessive production of ROS from these TLR4+ monocytes may lead to excessive injury of surrounding tissue and hence contribute to the pathological processes that lead to the development of advanced periductal fibrosis.

Source: The Journal of Infection in Developing Countries - August 30, 2023 Category: Infectious Diseases Authors: Kanin Salao, Chakrit Thapphan, Tran Duong Thai, Kiatichai Faksri, Sutas Suttiprapa, Sirikachorn Tangkawattana, Banchob Sripa B, Steven W Edwards Source Type: research