Icaritin attenuates recurrent spontaneous abortion in mice by modulating Treg/Th17 imbalance via TGF- β/SMAD signaling pathway

In conclusion, our study suggested that ICT ameliorated RSA by modulating Treg/Th17 cell imbalance via the TGF-β/SMAD signaling pathway. GENERAL SIGNIFICANCE: Our results highlighted the potential of ICT as a novel therapeutic agent for RSA, offering new insights into the underlying mechanisms and opening avenues for future research and clinical translation.PMID:37689142 | DOI:10.1016/j.bbamcr.2023.119574
Source: Biochimica et Biophysica Acta - Category: Biochemistry Authors: Source Type: research