N6 ‐methyladenosine‐modified circFUT8 competitively interacts with YTHDF2 and miR‐186‐5p to stabilize FUT8 mRNA to promote malignant progression in lung adenocarcinoma

ConclusionsThese findings identified a novel m6A-modified circFUT8 recognized and destabilized by YTHDF2, which competitively interacted with YTHDF2 and miR-186-5p to stabilize FUT8 mRNA to promote malignant progression in LUAD.

Source: Thoracic Cancer - September 6, 2023 Category: Cancer & Oncology Authors: Gaochao Dong, Yingkuan Liang, Bing Chen, Te Zhang, Hui Wang, Yuzhong Chen, Yijian Zhang, Feng Jiang, Yaping Wang Tags: ORIGINAL ARTICLE Source Type: research