Core decompression combined with local DFO administration loaded on polylactic glycolic acid scaffolds for the treatment of osteonecrosis of the femoral head: a pilot study

CONCLUSION: In short-term follow-up, combined core decompression and local DFO administration not only prevent the progression of ONFH but also reduces the rate of osteonecrosis significantly. However, future controlled studies are required to confirm the present results.TRIAL REGISTRATION: IRCT20161121031003N3, 16/04/2019.PMID:37670365 | DOI:10.1186/s40360-023-00682-x

Source: BMC Pharmacology and Toxicology - September 5, 2023 Category: Drugs & Pharmacology Authors: Kaveh Gharanizadeh Ali Mohammad Sharifi Hamed Tayyebi Razieh Heidari Shayan Amiri Sajad Noorigaravand Source Type: research