Sucrose analgesia for heel-lance procedures in neonates

CONCLUSIONS: Sucrose compared to control probably results in a reduction of PIPP scores 30 and 60 seconds after single heel lances (moderate-certainty evidence). Evidence is very uncertain about the effect of sucrose compared to NNS, breastfeeding, laser acupuncture, facilitated tucking, and the effect of sucrose + NNS compared to NNS in reducing pain. Sucrose compared to glucose, expressed breast milk, and skin-to-skin care shows little to no difference in pain scores. Sucrose combined with other nonpharmacologic interventions should be used with caution, given the uncertainty of evidence.PMID:37655530 | PMC:PMC10466459 | DOI:10.1002/14651858.CD014806
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research