Frequency of infiltrating regulatory T-cells in the portal tract of biliary atresia

ConclusionThe number of Tregs infiltrating the portal tract was higher in BA patients. However, the infiltration of lymphocytes was also generally increased. Tregs appear to be unsuccessful in suppressing progressive inflammation in BA patients, despite recruitment to local sites. Investigation of Treg function in the local environment is warranted.
Source: Pediatric Surgery International - Category: Surgery Source Type: research