Investigating In situ Expression of Neurotrophic Factors and Partner Proteins in Irreversible Pulpitis

In situ assessments of neurotrophic factors and their associated molecular partners have not been explored to date particularly in humans. The present investigation aims to explore the expressional dysregulation of neurotrophic factors (NGF, BDNF and NT4/5), their receptors (TrkA and TrkB) and their modulators (USP36 and Nedd4-2) directly in irreversibly inflamed human pulp tissues.
Source: Journal of Endodontics - Category: Dentistry Authors: Tags: Basic Research-Biology Source Type: research