Opioid-prescribing Practices in a Graduate Endodontic Clinic before and after Implementation of the Federal Schedule II Prescribing Mandate
Opioid prescriptions have the potential for misuse. In October 2014, the federal schedule II prescribing mandate reclassified hydrocodone combination products from schedule III to schedule II drugs that required a written prescription. The aim of this study was to evaluate the opioid-prescribing practices in a graduate endodontic clinic (GEC) before and after the mandate. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 12, 2019 Category: Dentistry Authors: Andrew M. Broadsword, Christine M. Sedgley, Richie Kohli, Al M. Best, Karan J. Replogle Tags: Clinical Research Source Type: research

A Correlation between Wnt/Beta-catenin Signaling and the Rate of Dentin Secretion
Odontoblasts produce dentin throughout life and in response to trauma. The purpose of this study was to identify the roles of endogenous Wnt signaling in regulating the rate of dentin accumulation. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 12, 2019 Category: Dentistry Authors: Yuan Zhao, Xue Yuan, Teresita Bellido, Jill A. Helms Tags: Basic Research Source Type: research

Insights into the October 2019 Issue of the Journal of Endodontics
Welcome to the October 2019 issue of the Journal of Endodontics (JOE)! We enjoy sharing with you some of our favorite articles in this issue. They cover the range from clinical trials to basic research and that reflects our editorial focus —to give you studies of importance for your next patient and to set the stage for treating our future patients with the latest effective procedures. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 12, 2019 Category: Dentistry Authors: Amir Azarpazhooh, Anibal R. Diogenes, Ashraf F. Fouad, Gerald N. Glickman, Mo K. Kang, Anil Kishen, Linda Levin, Robert S. Roda, Christine M. Sedgley, Franklin R. Tay, Kenneth M. Hargreaves Tags: Editorial Source Type: research

Outcome of Partial Pulpotomy in Cariously Exposed Posterior Permanent Teeth: A Systematic Review and Meta-analysis
The current systematic review and meta-analysis aimed to evaluate the success rate of partial pulpotomy in treating permanent posterior teeth with carious vital pulp exposure. A secondary aim was to assess the prognostic factors using a meta-regression. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 9, 2019 Category: Dentistry Authors: Firas Elmsmari, Xavier-Fructu ós Ruiz, Queralt Miró, Nancy Feijoo-Pato, Fernando Durán-Sindreu, Juan Gonzalo Olivieri Tags: Review Article Source Type: research

Endodontic Microsurgery Using Dynamic Navigation System: A Case Report
Dynamic navigation systems were introduced to facilitate dental implantology by improving the accuracy of dental implant positioning. Dynamic navigation integrates surgical instrumentation and radiologic images by using an optical positioning device controlled by a dedicated computerized interface. These features could help in reducing the risk of unintentional iatrogenic damage to nearby anatomic structures and perform minimally invasive or flapless surgery, leading to reduced patient postoperative discomfort and improved healing. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 9, 2019 Category: Dentistry Authors: Gianluca Gambarini, Massimo Galli, Luigi V. Stefanelli, Dario Di Nardo, Antonio Morese, Marco Seracchiani, Francesca De Angelis, Stefano Di Carlo, Luca Testarelli Tags: Case Report/Clinical Techniques Source Type: research

Histologic Evaluation of Regenerated Tissues in the Pulp Spaces of Teeth with Mature Roots at the Time of the Regenerative Endodontic Procedures
This report presents histologic findings with regard to regenerative tissues in the pulp spaces exposed after dental trauma in human mature maxillary incisor teeth successfully treated with REPs. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 9, 2019 Category: Dentistry Authors: Hakan Arslan, Yavuz Şahin, Hüseyin Sinan Topçuoğlu, Betül Gündoğdu Tags: Case Report/Clinical Techniques Source Type: research

Shear Bond Comparison between 4 Bioceramic Materials and Dual-cure Composite Resin
This study compared the bond strength between 4 bioceramic materials and a dual-cure composite resin. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 3, 2019 Category: Dentistry Authors: Kelley A. Hursh, Timothy C. Kirkpatrick, Jared W. Cardon, John A. Brewster, Steven W. Black, Van T. Himel, Kent A. Sabey Tags: Basic Research Source Type: research

Ingles Endodontics 7
The seventh edition of Ingle's Endodontics is a fantastic revision and update of 1 of the bibles of endodontics. This marks the 50th year since the first edition and fittingly a return to a bright yellow cover —a tribute to the late Dr John Ingle and his wife. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 31, 2019 Category: Dentistry Authors: Biraj Patel Tags: Book Review Source Type: research

Intentional Replantation with an Atraumatic Extraction System in Teeth with Extensive Cervical Resorption
External cervical resorption (ECR) often renders a tooth nonrestorable, especially if it extends deeply within the dental hard tissue. Intentional replantation is sometimes performed as the last resort to save the tooth but may limit conventional forceps extraction because of the high risk of periodontal ligament cell damage or crown fracture.This case report describes the intentional replantation of an upper central incisor with extensive ECR using an axial, atraumatic extraction system to save the otherwise hopeless tooth. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 30, 2019 Category: Dentistry Authors: Ralf Krug, Sebastian Soliman, Gabriel Krastl Tags: Case Report/Clinical Techniques Source Type: research

Canal Transportation and Centering Ability in Long Oval Canals: A Multidimentional Analysis
The purpose of this study was to evaluate and compare the centering ability and canal transportation of the ProTaper Next (PTN; Dentsply Maillefer, Ballaigues, Switzerland) and Self-adjusting File (SAF; ReDent-Nova, Ra'anana, Israel) systems in long oval root canals using cone-beam computed tomography imaging. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 29, 2019 Category: Dentistry Authors: Tousif Iqbal Nathani, Aatif Iqbal Nathani, Ajinkya M. Pawar, Moez Ismail Khakiani, Xavier-Fructu ós Ruiz, Juan Gonzalo Olivieri Tags: Basic Research Source Type: research

Insights into the September 2019 Issue of the Journal of Endodontics
Welcome to the September 2019 issue of the Journal of Endodontics (JOE)! We continue to receive great feedback about this new initiative, and we hope you look forward to reading this issue of JOE. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 25, 2019 Category: Dentistry Authors: Amir Azarpazhooh, Anibal R. Diogenes, Ashraf F. Fouad, Gerald N. Glickman, Mo K. Kang, Anil Kishen, Linda Levin, Robert S. Roda, Christine M. Sedgley, Franklin R. Tay, Kenneth M. Hargreaves Tags: Editorial Source Type: research

Editorial Board
(Source: Journal of Endodontics)
Source: Journal of Endodontics - August 25, 2019 Category: Dentistry Source Type: research

Table of Contents
(Source: Journal of Endodontics)
Source: Journal of Endodontics - August 25, 2019 Category: Dentistry Source Type: research

Guidelines for Authors and Reviewers
(Source: Journal of Endodontics)
Source: Journal of Endodontics - August 25, 2019 Category: Dentistry Source Type: research

QR Codes
(Source: Journal of Endodontics)
Source: Journal of Endodontics - August 25, 2019 Category: Dentistry Source Type: research

Associate Registry
(Source: Journal of Endodontics)
Source: Journal of Endodontics - August 25, 2019 Category: Dentistry Source Type: research

CE Registry
(Source: Journal of Endodontics)
Source: Journal of Endodontics - August 25, 2019 Category: Dentistry Source Type: research

Ultrasound Examination to Visualize and Trace Sinus Tracts of Endodontic Origin
The detection of a tooth with a sinus tract (ST) of endodontic origin and its pathway are conventionally assessed with a periapical radiograph and a gutta-percha cone introduced into its stoma. The aim of this study was to evaluate the possibility to detect STs and trace their route using ultrasound real-time examination. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 23, 2019 Category: Dentistry Authors: Elisabetta Cotti, Davide Musu, Alessandro Goddi, Claudia Dettori, Girolamo Campisi, Hagay Shemesh Tags: Clinical Research Source Type: research

Cervical Level Biological Repair of the Access Opening after Regenerative Endodontic Procedures: Three Cases with the Same Repair Pattern
This article describes the regenerative endodontic procedures applied in 3 cases of maxillary incisor necrosis that resulted in continuous root development, dentinal wall thickening, and cervical level biological repair of the access openings that was verified radiographically in 2 cases and clinically in 1 case. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 22, 2019 Category: Dentistry Authors: Antonis Chaniotis, Xenos Petridis Tags: Regenerative Endodontics Source Type: research

Evaluation of Physicochemical Properties of a New Calcium Silicate –based Sealer, Bio-C Sealer
Calcium silicate –based materials have been proposed as root canal sealers for root canal treatment. The aim of this study was to evaluate the physicochemical properties of a new calcium silicate–based sealer (Bio-C Sealer; Angelus, PR, Brazil) compared with a calcium silicate endodontic sealer (TotalFill BC Sea ler; FKG Dentaire SA, La Chaux-de-Fonds, Switzerland) and an epoxy resin sealer (AH Plus; Dentsply DeTrey, Konstanz, Germany). (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 22, 2019 Category: Dentistry Authors: Cristiane Lopes Zordan-Bronzel, Fernanda Ferrari Esteves Torres, Mario Tanomaru-Filho, Gisselle Moraima Ch ávez-Andrade, Roberta Bosso-Martelo, Juliane Maria Guerreiro-Tanomaru Tags: Basic Research Source Type: research

The 5-Year Survival Rate of Nonsurgical Endodontic Treatment: A Population-based Cohort Study in Korea
The purpose of the current population-based study was to analyze the 5-year survival rate of teeth that received nonsurgical endodontic treatment. Specifically, the variables affecting the 5-year survival rates of endodontically treated teeth were analyzed. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 19, 2019 Category: Dentistry Authors: Youngjun Kwak, Jungkyu Choi, Kiyeol Kim, Su-Jung Shin, Sunil Kim, Euiseong Kim Tags: Clinical Research Source Type: research

Root Canal Preparation Does Not Induce Dentinal Microcracks In  Vivo
This in  vivo study aimed to evaluate the development of dentinal microcracks after root canal preparation of contralateral premolars with rotary or hand instruments using micro–computed tomographic technology. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 14, 2019 Category: Dentistry Authors: Angambakkam Rajasekaran PradeepKumar, Hagay Shemesh, Durvasulu Archana, Marco A. Versiani, Manoel D. Sousa-Neto, Graziela B. Leoni, Yara T.C. Silva-Sousa, Anil Kishen Tags: Basic Research Source Type: research

Comparison of Cyclic Fatigue Resistance of 5 Heat-treated Nickel-titanium Reciprocating Systems in Canals with Single and Double Curvatures
The goal of this study was to compare the cyclic fatigue resistance of 5 heat-treated nickel-titanium files in reciprocating movement with the same tip size and different cross sections. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 13, 2019 Category: Dentistry Authors: Mohammad I. Al-Obaida, Khalid Merdad, Mohammed S. Alanazi, Hesham Altwaijry, Mohammad AlFaraj, Ali A. Alkhamis, Ebtissam M. Al-Madi Tags: Basic Research Source Type: research

Torsional Resistance of ProGlider, Hyflex EDM, and One G Glide Path Instruments
The present study aimed to compare the torsional resistance of ProGlider (Dentsply Sirona, Ballaigues, Switzerland), Hyflex EDM (Coltene-Whaledent, Altst ätten, Switzerland), and One G (Micro-Mega, Besancon, France) glide path instruments. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 10, 2019 Category: Dentistry Authors: U ğur İnan, Cangül Keskin Tags: Basic Research Source Type: research

Opioid-prescribing Habits of Practitioner and Educator Members of the American Association of Endodontists: Report of a National Survey
Dentists and physicians alike often prescribe opioids for dental pain management. The purpose of this study was to identify the common practices among United States endodontists for prescribing opioids to their patients. A descriptive, cross-sectional survey was developed to query 1000 American Association of Endodontists members from all 7 districts in the United States. The 20-question survey addressed provider demographics, types and frequency of medications prescribed, and clinical scenarios that compelled prescription-writing habits. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 9, 2019 Category: Dentistry Authors: Maha Alghofaily, Elaine Romberg, Sara Aldahmash, Patricia A. Tordik Tags: Case Report/Clinical Techniques Source Type: research

Vasoactive Intestinal Peptide Immunoregulatory Role at the Periapex: Associative and Mechanistic Evidences from Human and Experimental Periapical Lesions
In this study, we investigated (in a cause-and-effect manner) the potential involvement of VIP in the development of human and experimental periapical lesions. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 8, 2019 Category: Dentistry Authors: Michelle de Campos Soriani Azevedo, Thiago Pompermaier Garlet, Carolina Favaro Francisconi, Priscila Maria Colavite, Andr é Petenuci Tabanez, Jessica Lima Melchiades, Ana Paula Favaro Trombone, Charles Sfeir, Steven Little, Renato Menezes Silva, Gustavo Tags: Basic Research Source Type: research

Differences in Inflammation and Bone Resorption between Apical Granulomas, Radicular Cysts, and Dentigerous Cysts
Dental cysts can be of inflammatory (radicular cysts) or noninflammatory (dentigerous cysts) origin. Apical periodontitis is a necrosis of the pulp and infection of the root canal causing the development of apical granulomas or radicular cysts. The immunology of granuloma and cyst formation is important because modern root filling materials are immunologically active and can contribute to the resolution of apical granulomas. In contrast, radicular cysts often require apicectomy. A better understanding of the pathophysiology of inflammation and bone resorption in apical periodontitis could be the basis for developing new ro...
Source: Journal of Endodontics - August 7, 2019 Category: Dentistry Authors: Manuel Weber, Jutta Ries, Maike B üttner-Herold, Carol-Immanuel Geppert, Marco Kesting, Falk Wehrhan Tags: Clinical Research Source Type: research

Analysis of Fused Rooted Maxillary First and Second Molars with Merged and C-shaped Canal Configurations: Prevalence, Characteristics, and Correlations in a Saudi Arabian Population
The aims of this in  vivo cone-beam computed tomographic (CBCT) study were to evaluate the prevalence, characteristics, and correlations between the fused rooted maxillary first and second molars as well as their consequent merged and C-shaped canals in a Saudi Arabian population. (Source: Journal of Endodontics)
Source: Journal of Endodontics - August 1, 2019 Category: Dentistry Authors: Mohammed Mashyakhy, Hemant Ramesh Chourasia, Ahmad Jabali, Abdulmajeed Almutairi, Gianluca Gambarini Tags: Clinical Research Source Type: research

A Horizontal Sequential Cutting Method to Estimate the Effectiveness of Dentin Disinfection by Using Confocal Laser Scanning Microscopy
This study aimed to develop a technique to create sequential slices, allowing the fluorescent visualization of bacterial viability in all parts of an infected dentin. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 31, 2019 Category: Dentistry Authors: Taisuke Hasegawa, Shoji Takenaka, Rika Wakamatsu, Tatsuya Ohsumi, Hisanori Domon, Hayato Ohshima, Yutaka Terao, Yuichiro Noiri Tags: Basic Research Source Type: research

Resolvin E1 Ameliorates Pulpitis by Suppressing Dental Pulp Fibroblast Activation in a Chemerin Receptor 23-dependent Manner
Timely resolution of pulp inflammation is a prerequisite for the healing of inflamed dental pulp. Stromal cells, particularly fibroblasts, play a critical role in the inflammation resolution process. Resolvin E1 (RvE1) is a lipid-derived endogenous proresolution molecule that mediates this resolution process. In the present study, we investigated the effects of RvE1 on dental fibroblasts during the pathogenesis of pulpitis. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 25, 2019 Category: Dentistry Authors: Huaxing Xu, Jie Chen, Jianping Ge, Kun Xia, Shuo Tao, Yue Su, Qi Zhang Tags: Basic Research Source Type: research

Editorial Board
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Source Type: research

Table of Contents
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Source Type: research

Guidelines for Authors and Reviewers
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Source Type: research

QR Codes
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Source Type: research

Insights into the August 2019 Issue of the Journal of Endodontics
Welcome to the August 2019 issue of the Journal of Endodontics (JOE)! We have received terrific feedback about this new initiative, and we hope you look forward to reading this issue in JOE. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Authors: Amir Azarpazhooh, Anibal R. Diogenes, Ashraf F. Fouad, Gerald N. Glickman, Mo K. Kang, Anil Kishen, Linda Levin, Robert S. Roda, Christine M. Sedgley, Franklin R. Tay, Kenneth M. Hargreaves Tags: Editorial Source Type: research

Associate Registry
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Source Type: research

Foundation for Endodontics
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Source Type: research

Donor Honor Roll
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Source Type: research

MicroRNA Expression Profiles in External Cervical Resorption
This study characterized microRNA (miRNA) expression patterns of human tissues from ECR lesions and identified potential messenger RNA targets and pathways. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Authors: Mary T. Pettiette, Shaoping Zhang, Antonio J. Moretti, Steven J. Kim, Afsar R. Naqvi, Salvador Nares Tags: Clinical Research Source Type: research

Association between Pulp Stones and Kidney Stones: A Systematic Review and Meta-analysis
A systematic review and meta-analysis were performed to evaluate the association between pulp stones and kidney stones. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 24, 2019 Category: Dentistry Authors: Marilisa Carneiro Le ão Gabardo, Letícia Maira Wambier, Juliana Schaia Rocha, Erika Calvano Küchler, Rafaela Mariana de Lara, Denise Piotto Leonardi, Manoel Damião Sousa-Neto, Flares Baratto-Filho, Edgard Michel-Crosato Tags: Review Article Source Type: research

3-dimensional Ability Assessment in Removing Root  Filling Material from Pair-matched Oval-shaped Canals Using Thermal-treated Instruments
The purpose of this study was to evaluate the ability of the XP-endo Shaper instrument (FKG Dentaire, La Chaux-de-Fonds, Switzerland) during the removal of root fillings from oval-shaped canals. M-Wire Reciproc and Reciproc Blue systems (VDW, Munich, Germany) were used as reference instruments for comparison, and micro –computed technology was used as an analytical tool. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 23, 2019 Category: Dentistry Authors: Gustavo De-Deus, Felipe Gon çalves Belladonna, Arthur de Siqueira Zuolo, Daniele Moreira Cavalcante, Marco Simões Carvalho, Alessandra Marinho, Erick Miranda Souza, Ricardo Tadeu Lopes, Emmanuel João Nogueira Leal Silva Tags: Basic Research Source Type: research

The Effect of Calcium Hydroxide and Nano –calcium Hydroxide on Microhardness and Superficial Chemical Structure of Root Canal Dentin: An Ex Vivo Study
Calcium hydroxide (CH) and nano –calcium hydroxide (NCH) as intracanal medicaments may affect the physical and chemical properties of dentin. The aim of this investigation was to evaluate the effects of CH and NCH on the microhardness and superficial chemical structure of radicular dentin. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 22, 2019 Category: Dentistry Authors: Mandana Naseri, Leila Eftekhar, Farshid Gholami, Mohammad Atai, Omid Dianat Tags: Basic Research Source Type: research

Effect of Heated Sodium Hypochlorite on the Viscoelastic Properties of Dentin Evaluated Using Dynamic Mechanical Analysis
This study aimed to investigate the effect of the immersion of standardized dentin bars in 5% sodium hypochlorite (NaOCl) solutions at 60 °C and 80°C on their viscoelastic properties using dynamic mechanical analysis. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 17, 2019 Category: Dentistry Authors: Nikoletta Kafantari, Kishor Gulabivala, George Georgiou, Jonathan Knowles, Yuan-Ling Ng Tags: Basic Research Source Type: research

Erratum
to Effectiveness of Gutta-percha/Sealer Removal during Retreatment of Extracted Human Molars Using the GentleWave System [Journal of Endodontics 45 (2019) 808 –812] (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 11, 2019 Category: Dentistry Tags: Erratum Source Type: research

Vital Pulp Therapy as a Conservative Approach for Management of Invasive Cervical Root Resorption: A  Case Series
Clear treatment guidelines with predictable outcomes for invasive cervical root  resorption (ICRR) do not exist. Recent studies show that an internal approach for the excavation and repair of resorptive lacunae using bioactive materials might be preferred over external surgical approaches in cases with extensive ICRR. The procedure appears to interrupt and stop the resorptive process and preserves the periodontium. The aim of this case series was to report on the clinical and radiographic outcomes in cases with ICRR treated with vital pulp therapy techniques using calcium-enriched mixture cement. (Source: Jo...
Source: Journal of Endodontics - July 11, 2019 Category: Dentistry Authors: Saeed Asgary, Mahdieh Nourzadeh, Prashant Verma, M. Lamar Hicks, Ali Nosrat Tags: Case Report/Clinical Techniques Source Type: research

Outcome of Endodontic Retreatment Using 2 Root Canal Irrigants and Influence of Infection on Healing as Determined by a Molecular Method: A Randomized Clinical Trial
This study compared the clinical and radiographic outcome of endodontic retreatment of teeth with apical periodontitis using either 1% sodium hypochlorite (NaOCl) or 2% chlorhexidine digluconate (CHX) as the irrigant. The influence of residual infection detected by a molecular method on the outcome was also examined. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 9, 2019 Category: Dentistry Authors: Homan Zandi, Nikola Petronijevic, Ibrahimu Mdala, Anne K. Kristoffersen, Morten Enersen, Isabela N. R ôças, José F. Siqueira, Dag Ørstavik Tags: CONSORT Randomized Clinical Trial Source Type: research

Dynamics of Bone Loss in Cases with Acute or Chronic Apical Abscess
The objective of this study was to evaluate the size and pattern of bone loss in patients with acute apical abscess (AAA) and chronic apical abscess (CAA) using cone-beam computed tomographic images. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 4, 2019 Category: Dentistry Authors: Poorya Jalali, Mehrnaz Tahmasbi, Robert A. Augsburger, N. Karang Khalilkhani, Kian Daghighi Tags: Clinical Research Source Type: research

Effect of a Residual Biofilm on Release of Transforming Growth Factor β1 from Dentin
Several studies have reported regeneration of the pulp-dentin complex when treating noninfected root canal systems. However, current protocols applied to infected root canal systems are much less predictable for the formation of dentin. Converging lines of evidence implicate residual biofilm as an important factor for these variable histologic outcomes. Here we studied the effect of a residual polymicrobial biofilm on the release of transforming growth factor beta 1 (TGF- β1) from dentin. We hypothesized that the presence of bacterial biofilm attenuates the release of bioactive molecules from dentin. (Source: Journal of Endodontics)
Source: Journal of Endodontics - July 2, 2019 Category: Dentistry Authors: Ritter Cameron, Espitia Claudia, Wu Ping, Son Erin, Nikita B. Ruparel Tags: Regenerative Endodontics Source Type: research

Editorial Board
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 1, 2019 Category: Dentistry Source Type: research

Table of Contents
(Source: Journal of Endodontics)
Source: Journal of Endodontics - July 1, 2019 Category: Dentistry Source Type: research