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Cost-effectiveness of Different Post-retained Restorations
Dentists can choose between metal and fiber  post systems to provide post-retained restorations. The risk of tooth loss and other complications differs between different post systems, as do the initial treatment costs. We aimed to assess the cost-effectiveness of (1) cast metal (MC), (2) preformed metal (MP), (3) glass fiber (GF), and (4) ca rbon fiber (CF) post-retained restorations. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 23, 2017 Category: Dentistry Authors: Falk Schwendicke, Michael Stolpe Tags: Clinical Research Source Type: research

Coronal and Intraradicular Appearances Affect Radiographic Perception of the Periapical Region
The influence of the radiographic appearances of the coronal and intraradicular areas on periapical radiographic interpretation has been minimally evaluated in dentistry and endodontics. The purpose of this study was to evaluate the effects that the coronal and intraradicular radiographic appearance has on endodontists' radiographic interpretations of periapical areas. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 23, 2017 Category: Dentistry Authors: Julie W. Strong, Karl F. Woodmansey, John A. Khademi, John F. Hatton Tags: Clinical Research Source Type: research

Endodontics, Endodontic Retreatment, and Apical Surgery Versus Tooth Extraction and Implant Placement: A Systematic Review
The aim of this systematic review was to answer the following clinical question: Which is the best treatment option for a pulpally involved tooth? (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 23, 2017 Category: Dentistry Authors: Anna Ch ércoles-Ruiz, Alba Sánchez-Torres, Cosme Gay-Escoda Tags: Review Article Source Type: research

Cobalt Chloride Enhances the Stemness of Human Dental Pulp Cells
Hypoxia is a factor in controlling stem cell stemness. We investigated if cobalt chloride (CoCl2), a chemical agent that mimics hypoxia in  vitro, affected human dental pulp cell (hDPC) stemness by examining cell proliferation, stem cell marker expression, and osteogenic differentiation. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 23, 2017 Category: Dentistry Authors: Kantaporn Laksana, Sireerat Sooampon, Prasit Pavasant, Wannakorn Sriarj Tags: Basic Research Source Type: research

Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double-blind Randomized Controlled Trial
The present clinical trial aimed to evaluate and compare the effect of a single pretreatment dose of ketorolac (20  mg), prednisolone (30 mg), and placebo on postendodontic pain in patients undergoing endodontic therapy for irreversible pulpitis or pulpal necrosis using a visual analog scale. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 18, 2017 Category: Dentistry Authors: R. Praveen, Sophia Thakur, M. Kirthiga Tags: CONSORT Randomized Clinical Trial Source Type: research

A Randomized Clinical Trial Comparing 2 Ibuprofen Formulations in Patients with Acute Odontogenic Pain
Ibuprofen sodium dihydrate, a new formulation of ibuprofen, was introduced with the claim of faster onset of analgesia. Most of the data on this new ibuprofen formulation are drawn from studies using the oral surgery model. Because this model differs significantly from the endodontic pain model, we conducted a study comparing ibuprofen sodium dihydrate with conventional ibuprofen acid in endodontic pain patients. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 18, 2017 Category: Dentistry Authors: Tanjit Taggar, Di Wu, Asma A. Khan Tags: CONSORT Randomized Clinical Trial Source Type: research

Cytotoxicity, Biocompatibility, and Biomineralization of the New High-plasticity MTA Material
Mineral trioxide aggregate (MTA) has excellent biological properties, but its handling properties have been criticized for both ProRoot MTA (Tulsa Dental Products, Tulsa, OK) and white MTA-Angelus (MTA-Ang; Angelus Ind ústria de Produtos Odontológicos S/A, Londrina, PR, Brazil). Angelus MTA HP (high plasticity) (Angelus Indústria de Produtos Odontológicos S/A) has been introduced recently. Considering the importance of biological properties of materials that will be in contact with the tissues, this study eval uated the cytotoxicity, biocompatibility, and biomineralization of MTA HP compared wit...
Source: Journal of Endodontics - March 18, 2017 Category: Dentistry Authors: Luciano Tavares Angelo Cintra, Francine Benetti, Índia Olinta de Azevedo Queiroz, Juliana Maria de Araújo Lopes, Sandra Helena Penha de Oliveira, Gustavo Sivieri Araújo, João Eduardo Gomes-Filho Tags: Basic Research Source Type: research

Bioactive Molecule Delivery Systems for Dentin-pulp Tissue Engineering
Regenerative endodontic procedures use bioactive molecules (BMs), which are active signaling molecules that initiate and maintain cell responses and interactions. When applied in a bolus form, they may undergo rapid diffusion and denaturation resulting in failure to induce the desired effects on target cells. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 18, 2017 Category: Dentistry Authors: Suja Shrestha, Anil Kishen Tags: Review Article Source Type: research

Effect of Using Different Vehicles on the Physicochemical, Antimicrobial, and Biological Properties of White Mineral Trioxide Aggregate
This study evaluated the physicochemical, antimicrobial, and biological properties of white mineral trioxide aggregate (MTA) mixed with aqueous and propylene glycol extracts of Arctium lappa L. and Casearia sylvestris Sw. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 18, 2017 Category: Dentistry Authors: Bruno Cavalini Cavenago, Aldo Enrique del Carpio-Perochena, Ronald Ordinola-Zapata, Carlos Estrela, Gustavo Pompermaier Garlet, Mario Tanomaru-Filho, Paulo Henrique Weckwerth, Flaviana Bombarda de Andrade, Marco Antonio Hungaro Duarte Tags: Basic Research Source Type: research

First Evidence for Regeneration of the Periodontium to Mineral Trioxide Aggregate in Human Teeth
The aim of this study was to elucidate whether the use of mineral trioxide aggregate (MTA) in endodontic therapy in human teeth leads to the same regeneration of the apical tissues as observed in animals. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 18, 2017 Category: Dentistry Authors: Andreas Bartols, Eleni Roussa, Winfried Walther, Christof E. D örfer Tags: Clinical Research Source Type: research

Push-out Bond Strength of Fast-setting Mineral Trioxide Aggregate and Pozzolan-based Cements: ENDOCEM MTA and ENDOCEM Zr
The present study investigated the root canal dentin bond strength of 2 newly developed fast-setting mineral trioxide aggregate (MTA) and pozzolan-based cements: ENDOCEM MTA (Maruchi, Wonju, Korea) and ENDOCEM Zr (Maruchi). White MTA (Angelus, Londrina, Brazil) was used as the reference material for comparison. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Emmanuel Jo ão Nogueira Leal Silva, Nancy Kudsi Carvalho, Marta Reis da Costa Labanca Guberman, Marina Prado, Plinio Mendes Senna, Erick M. Souza, Gustavo De-Deus Tags: Basic Research Source Type: research

Clinical and Radiographic Characteristics of Vertical Root Fractures in Endodontically and Nonendodontically Treated Teeth
A vertical root fracture (VRF) is a root fracture extending along the longitudinal axis of roots and is often noted in endodontically treated teeth. However, the clinical and radiographic characteristics of VRFs are not completely known. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Wan-Chuen Liao, Yi-Ling Tsai, Chen-Ying Wang, Mei-Chi Chang, Wei-Ling Huang, Hsueh-Jen Lin, Hsin-Cheng Liu, Chiu-Po Chan, Shu-Hui Chang, Jiiang-Huei Jeng Tags: Clinical Research Source Type: research

Shaping Ability of Reciproc, WaveOne GOLD, and HyFlex EDM Single-file Systems in Simulated S-shaped Canals
The aim of the present study was to compare the shaping ability of Reciproc (RPC; VDW, Munich, Germany), HyFlex EDM (HEDM; Coltene/Whaledent AG, Altst ätten, Switzerland), and WaveOne GOLD (WOG; Dentsply Maillefer, Ballaigues, Switzerland) nickel-titanium (NiTi) files made of different NiTi alloys in S-shaped simulated canals. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Taha Özyürek, Koray Yılmaz, Gülşah Uslu Tags: Basic Research Source Type: research

Efficacy of Different Cone-beam Computed Tomographic Protocols in the Identification of Mesiobuccal Canals of Maxillary First Molars: A Tomographic and Ex  Vivo Study
Complementary methods of anatomic diagnosis, including cone-beam computed tomographic (CBCT) imaging, may be useful in the diagnosis of mesiobuccal (MB) canals of maxillary molars. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: J éssica Vavassori de Freitas, Flares Baratto-Filho, Beatriz Serrato Coelho, Flávia Sens Fagundes Tomazinho, Bruno Monguilhott Crozeta, Manoel Damião de Sousa Neto, Marilisa Carneiro Leão Gabardo Tags: Basic Research Source Type: research

Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway
This study aimed to evaluate the potential alterations of autophagic pathway during anti-osteoclastogenic effects by MTA in  vitro and investigate their underlying mechanisms. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Xue Cheng, Lingxin Zhu, Jie Zhang, Jingjing Yu, Shan Liu, Fengyuan Lv, Ying Lin, Guojing Liu, Bin Peng Tags: Basic Research Source Type: research

Outcomes of Endodontic Microsurgery Using a Microscope and Mineral Trioxide Aggregate: A Prospective Cohort Study
The aim of this study was to investigate the outcome of endodontic microsurgery and analyze the prognostic factors. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Zu-Hua Wang, Ming-Ming Zhang, Ji Wang, Lan Jiang, Yu-Hong Liang Tags: Clinical Research Source Type: research

Microguided Endodontics: Accuracy of a Miniaturized Technique for Apically Extended Access Cavity Preparation in Anterior Teeth
The aim of this study was to assess the accuracy of guided endodontics in mandibular anterior teeth by using miniaturized instruments. This technique is designed to treat teeth with pulp canal calcifications and narrow roots by using a printed template that guides a bur to the calcified root canal. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Thomas Connert, Marc S. Zehnder, Roland Weiger, Sebastian K ühl, Gabriel Krastl Tags: Basic Research Source Type: research

Investigation of Human Dental Pulp Cells on a Potential Injectable Poly(lactic-co-glycolic acid) Microsphere Scaffold
Poly(lactic-co-glycolic acid) (PLGA) has been extensively explored in the tissue engineering field with good biocompatibility and biodegradability. PLGA microspheres' injectable potency makes it highly desirable in dentin-pulp complex regeneration. Therefore, we investigated the cell adhesion, proliferation, odontogenic differentiation, and matrix mineralization of human dental pulp cells (HDPCs) on a PLGA microsphere scaffold. We hypothesized that this scaffold might be suitable for dentin-pulp complex regeneration. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Huiru Zou, Guanhua Wang, Fang Song, Xudong Shi Tags: Basic Research Source Type: research

A Survey of Cone-beam Computed Tomographic Use among Endodontic Practitioners in the United States
Cone-beam computed tomographic (CBCT) imaging is an emerging technology for clinical endodontic practice. The aim of this study was to investigate the acceptance, accessibility, and usage of CBCT imaging among American Association of Endodontists members in the United States by means of an online survey. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Frank C. Setzer, Nathan Hinckley, Meetu R. Kohli, Bekir Karabucak Tags: Clinical Research Source Type: research

Why Biphasic? Assessment of the Effect on Cell Proliferation and Expression
Tricalcium silicate (TCS) –based materials are used in endodontics because they are hydraulic and interact with blood, tissue fluids, and phosphate-based root canal irrigants, resulting in biomineralization. Newer-generation materials are biphasic; calcium phosphate is added to the TCS; thus, the material has 2 cementitiou s phases. The effect of this addition is not known; thus, the aim of this study was to characterize biphasic cements and assess cellular proliferation and expression. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Pierre Schembri-Wismayer, Josette Camilleri Tags: Basic Research Source Type: research

The Effect of the Dental Operating Microscope on the Outcome of Nonsurgical Root Canal Treatment: A Retrospective Case-control Study
The aim of the current investigation was to assess the effect of the use of a dental operating microscope on the outcome of nonsurgical root canal treatment (NS RCT) while treating the mesiobuccal (MB) root of the maxillary first molar. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 11, 2017 Category: Dentistry Authors: Navid Khalighinejad, Anita Aminoshariae, James C. Kulild, Kristin A. Williams, Jeannie Wang, Andre Mickel Tags: Clinical Research Source Type: research

A Novel Model for Evaluating the Flow of Endodontic Materials Using Micro –computed Tomography
Flow and filling ability are important properties of endodontic materials. The aim of this study was to propose a new technique for evaluating flow using micro –computed tomographic (μCT) imaging. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 3, 2017 Category: Dentistry Authors: Mario Tanomaru-Filho, Fernanda Ferrari Esteves Torres, Roberta Bosso-Martelo, Gisselle Moraima Ch ávez-Andrade, Idomeo Bonetti-Filho, Juliane Maria Guerreiro-Tanomaru Tags: Basic Research Source Type: research

Antibacterial Efficacy of Octenisept, Alexidine, Chlorhexidine, and Sodium Hypochlorite against Enterococcus faecalis Biofilms
The purpose of this study was to evaluate the antibacterial effectiveness of Octenisept (OCT; Sch ülke& Mayr GmBH, Norderstedt, Germany), 1% alexidine (ALX) (Santa Cruz Biotechnology, Inc, Santa Cruz, CA), and 2% chlorhexidine (CHX) against Enterococcus faecalis biofilm using confocal laser scanning microscopy. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 27, 2017 Category: Dentistry Authors: Sundus Bukhary, Hanan Balto Tags: Basic Research Source Type: research

An Approach for a Mathematical Description of Human Root Canals by Means of Elementary Parameters
Root canal geometry is an important factor for instrumentation and preparation of the canals. Curvature, length, shape, and ramifications need to be evaluated in advance to enhance the success of the treatment. Therefore, the present study aimed to design and realize a method for analyzing the geometric characteristics of human root canals. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 27, 2017 Category: Dentistry Authors: Martin Dannemann, Michael Kucher, Jasmin Kirsch, Alexander Binkowski, Niels Modler, Christian Hannig, Marie-Theres Weber Tags: Review Article Source Type: research

Human and Swine Dental Pulp Stem Cells Form a Vascularlike Network after Angiogenic Differentiation in Comparison with Endothelial Cells: A Quantitative Analysis
The aim of this study was to quantify vascular network formation capacity after angiogenic induction of human and swine dental pulp stem cells (DPSCs) in comparison with endothelial cells. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 27, 2017 Category: Dentistry Authors: Hacer Aksel, George T.-J. Huang Tags: Regenerative Endodontics Source Type: research

Apically Extruded Debris after Retreatment Procedure with Reciproc, ProTaper Next, and Twisted File Adaptive Instruments
The aim of this study was to compare the amount of debris extruded from the apex during retreatment procedures with ProTaper Next (PTN; Dentsply Maillefer, Ballaigues, Switzerland), Reciproc (RCP; VDW, Munich, Germany), and Twisted File Adaptive (TFA; SybronEndo, Orange, CA) files and the duration of these retreatment procedures. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 27, 2017 Category: Dentistry Authors: Koray Y ılmaz, Taha Özyürek Tags: Basic Research Source Type: research

Role of Protein Phosphatase 1 in Angiogenesis and Odontoblastic Differentiation of Human Dental Pulp Cells
The aims of this study were to examine the immunolocalization of protein phosphatase 1 (PP1) in developing mouse pulp tissue and to explore the role of PP1 in odontoblastic differentiation and in  vitro angiogenesis in human dental pulp cells (HDPCs). (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Ji-Youn Kim, Duk-Su Kim, Q-Schick Auh, Jin-Kyu Yi, Sung Ung Moon, Eun-Cheol Kim Tags: Basic Research Source Type: research

Decellularized Matrix Derived from Neural Differentiation of Embryonic Stem Cells Enhances the Neurogenic Potential of Dental Follicle Stem Cells
This study investigated whether neural differentiation of DFSCs can be enhanced by culture on decellularized matrix substrata (NSC-DECM) derived from neurogenesis of human embryonic stem cells (hESCs). (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Boon Chin Heng, Ting Gong, Shuai Wang, Lee Wei Lim, Wutian Wu, Chengfei Zhang Tags: Regenerative Endodontics Source Type: research

Biocompatibility Investigation of New Endodontic Materials Based on Nanosynthesized Calcium Silicates Combined with Different Radiopacifiers
The aim of this article was to analyze biocompatibility and bioactivity of new endodontic materials on the basis of nanosynthesized calcium silicates (ALBO-MPCA1 and ALBO-MPCA2) combined with different radiopacifiers in comparison with MTA+. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Bojana Cetenovic, Bogomir Prokic, Sasa Vasilijic, Biljana Dojcinovic, Marko Magic, Vukoman Jokanovic, Dejan Markovic Tags: Basic Research Source Type: research

Binary Decision Trees for Preoperative Periapical Cyst Screening Using Cone-beam Computed Tomography
Cone-beam computed tomographic (CBCT) analysis allows for 3-dimensional assessment of periradicular lesions and may facilitate preoperative periapical cyst screening. The purpose of this study was to develop and assess the predictive validity of a cyst screening method based on CBCT volumetric analysis alone or combined with designated radiologic criteria. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Brandon Pitcher, Ali Alaqla, Marcel Noujeim, James A. Wealleans, Georgios Kotsakis, Vanessa Chrepa Tags: Clinical Research Source Type: research

Effect of Platelet-rich Fibrin on Odontoblastic Differentiation in Human Dental Pulp Cells Exposed to Lipopolysaccharide
Platelet-rich fibrin (PRF), as an autologous fibrin matrix, is known to contain platelets, leukocytes, and growth factors to control inflammation and to facilitate the healing process. The purpose of this study was to investigate the effects of PRF on odontoblastic differentiation in human dental pulp cells (HDPCs) treated with lipopolysaccharide (LPS). (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Jae-Hwan Kim, Su-Mi Woo, Nam-Ki Choi, Won-Jae Kim, Seon-Mi Kim, Ji-Yeon Jung Tags: Basic Research Source Type: research

Prevalence of Apical Periodontitis in Patients with Inflammatory Bowel Diseases: A Retrospective Clinical Study
We evaluated the prevalence of apical periodontitis (AP) and the oral health status in patients with inflammatory bowel diseases (IBDs) treated with immunomodulators, with particular attention to biologic medications (BMs). (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Vanessa Piras, Paolo Usai, Silvia Mezzena, Marta Susnik, Francesca Ideo, Elia Schirru, Elisabetta Cotti Tags: Clinical Research Source Type: research

Apical Transportation, Centering Ratio, and Volume Increase after Manual, Rotary, and Reciprocating Instrumentation in Curved Root Canals: Analysis by Micro-computed Tomographic and Digital Subtraction Radiography
This study aimed to evaluate apical transportation (AT), centering ratio (CR), and volume increase (VI) produced after instrumentation of mesiobuccal canals of maxillary molars with hand files, rotary, and reciprocating instruments using micro –computed tomographic (micro-CT) imaging and to demonstrate the ability of digital subtraction radiography (DSR) to evaluate AT. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Caroline Zanesco, Marcus Vinicius Reis S ó, Sabrina Schmidt, Vania Regina Camargo Fontanella, Renata Grazziotin-Soares, Fernando Branco Barletta Tags: Basic Research Source Type: research

The Effect of Foraminal Enlargement of Necrotic Teeth with a Continuous Rotary System on Postoperative Pain: A Randomized Controlled  Trial
This single-blind, randomized controlled trial aimed to evaluate whether foraminal enlargement (FE) with a continuous rotary system during endodontic treatment causes more postoperative pain than nonforaminal enlargement (NFE). (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Ibrahim Ethem Yaylali, Anil Teke, Yasar Meric Tunca Tags: CONSORT Randomized Clinical Trial Source Type: research

Incidence of Dentinal Defects on the External Apical Root Surface after Instrumentation with WaveOne Reciprocating Files at Different Working Lengths
The aim of this in  vitro study was to identify the formation of dentinal defects on the external apical root surface of teeth instrumented at different working lengths by using WaveOne reciprocating files. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Marcela de Arruda Bitencourt, Daniel Guimar ães Pedro Rocha, Carlos Eduardo da Silveira Bueno Tags: Basic Research Source Type: research

Influence of Diabetes in the Development of Apical Periodontitis: A Critical Literature Review of Human Studies
The aim of this study was to perform a critical review of the literature that investigated the association between diabetes and apical periodontitis. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Authors: Camilla dos Santos Tib úrcio-Machado, Mariana De Carlo Bello, Juliana Maier, Carlos Frederico Brilhante Wolle, Carlos Alexandre Souza Bier Tags: Review Article Source Type: research

Editorial Board
(Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Source Type: research

Table of Contents
(Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Source Type: research

Associate Registry
(Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Source Type: research

CE Registry
(Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Source Type: research

AAE17 Abstracts of Research
(Source: Journal of Endodontics)
Source: Journal of Endodontics - February 23, 2017 Category: Dentistry Source Type: research

Micro –Computed Tomography Assessment of Dentinal Micro-cracks after Root Canal Preparation with TRUShape and Self-Adjusting File Systems
The aim of the present study was to evaluate the percentage frequency of dentinal micro-cracks observed after root canal preparation with TRUShape and Self-Adjusting File (SAF) systems by means of micro –computed tomography imaging analysis. A conventional full-sequence rotary system (BioRace) and a single-file reciprocation system (Reciproc) were used as reference techniques for comparison because of their known assertive cutting efficiency. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Mario Luis Zuolo, Gustavo De-Deus, Felipe Gon çalves Belladonna, Emmanuel João Nogueira Leal da Silva, Ricardo Tadeu Lopes, Erick Miranda Souza, Marco Aurélio Versiani, Alexandre Augusto Zaia Tags: Basic Research Source Type: research

Rac1 Regulates the Proliferation, Adhesion, Migration, and Differentiation of MDPC-23 Cells
Stem cells are responsible for replacing damaged pulp tissue; therefore, promoting their survival and inducing their adhesion to dentin are vital. As a member of the Rho family of guanosine triphosphatases, Rac1 is an important regulator of osteoblast functions. However, little is  known about its role in regenerative endodontic procedures. The current study examined the role of Rac1 in the proliferation, migration, and odontoblastic differentiation of MDPC-23 cells. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Jing Ren, Guobin Liang, Li Gong, Bing Guo, Hongwei Jiang Tags: Regenerative Endodontics Source Type: research

Detection of Fractured Endodontic Instruments in Root Canals: Comparison between Different Digital Radiography Systems and Cone-beam Computed Tomography
This study compared the detection of fractured instruments in root canals with and without filling by periapical radiographs from 3 digital systems and cone-beam computed tomographic (CBCT) images with different resolutions. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Ana Caroline Ramos Brito, Francielle Silvestre Verner, Rafael Binato Junqueira, Mayra Cristina Yamasaki, Polyane Mazucato Queiroz, Deborah Queiroz Freitas, Christiano Oliveira-Santos Tags: Clinical Research Source Type: research

Dental Pulp Tissue Regeneration Using Dental Pulp Stem Cells Isolated and Expanded in Human Serum
Dental pulp –derived stem cells (DPSCs) have the potential to regenerate dentin and dental pulp tissue because of their differentiation capacity and angiogenic properties. However, for regenerative approaches to gain regulatory and clinical acceptance, protocols are needed to determine more feasible ways to c ultivate DPSCs, namely, without the use of xenogeneic-derived components (animal sera) and exogenous growth factors. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Evandro Piva, Susan A. Tarl é, Jacques E. Nör, Duohong Zou, Elizabeth Hatfield, Tyler Guinn, Emily J. Eubanks, Darnell Kaigler Tags: Regenerative Endodontics Source Type: research

Are Premixed Calcium Silicate –based Endodontic Sealers Comparable to Conventional Materials? A Systematic Review of In Vitro Studies
This study aimed to compare the physicochemical and biological properties of premixed calcium silicate –based endodontic sealers with other conventional root canal filling materials by systematically reviewing laboratory studies. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Luiza Helena Silva Almeida, Rafael Ratto Moraes, Renata Dornelles Morgental, Fernanda Geraldo Pappen Tags: Review Article Source Type: research

Comparison of Cyclic Fatigue Resistance of WaveOne and WaveOne Gold Small, Primary, and Large Instruments
To compare the cyclic fatigue of resistance of WaveOne (WO; Dentsply Maillefer, Ballaigues, Switzerland) and WaveOne Gold (WOG, Dentsply Maillefer) small, primary, and large instruments in simulated root canals. Each instrument was rotated until fracture occurred. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Mehmet Ad ıgüzel, Ismail Davut Capar Tags: Basic Research Source Type: research

A Micro –Computed Tomography Evaluation of the Shaping Ability of Two Nickel-Titanium Instruments, HyFlex EDM and ProTaper Next
The aim of this study was to evaluate and compare, by means of micro –computed tomography imaging, the shaping ability of ProTaper Next (PTN) and the novel HyFlex EDM (HFEDM) instruments. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Pier Matteo Venino, Claudio Luigi Citterio, Alberto Pellegatta, Marta Ciccarelli, Marcello Maddalone Tags: Basic Research Source Type: research

Dentinal Tubule Penetration of a Calcium Silicate –based Root Canal Sealer with Different Obturation Methods
The purpose of this study was to investigate the depths of penetration of a calcium silicate –based sealer in dentinal tubules by using 3 different obturation methods. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Ji Wook Jeong, Anna DeGraft-Johnson, Samuel O. Dorn, Peter M. Di Fiore Tags: Basic Research Source Type: research

Clinical Outcomes after Intentional Replantation of Periodontally Involved Teeth
Periodontal involvement has been thought to be a contraindication for intentional replantation. This retrospective study aimed to assess clinical outcomes after intentional replantation of teeth with periodontal involvement and to explore potential predictors of outcomes. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 15, 2017 Category: Dentistry Authors: Sin-Yeon Cho, Seung-Jong Lee, Euiseong Kim Tags: Clinical Research Source Type: research