In vivo Metabolism of Nifurtimox and the Drug-Drug Interaction Potential Including its Major Metabolites
CONCLUSION: This contemporary analysis of the complex metabolite profile and associated exposures emerging after oral dosing of nifurtimox in rats and humans, together with the expected low risk for clinically relevant DDIs, expands the understanding of this important anti-trypanosomal drug.PMID:37592798 | DOI:10.2174/1389200224666230817114758
Source: Current Drug Metabolism - Category: Drugs & Pharmacology Authors: Simone I Schulz Dieter Lang Gabriele Schmuck Michael Gerisch Michaela Bairlein Robert Fricke Heino Stass Source Type: research