Proanthocyanidin A2 attenuates the activation of hepatic stellate cells by activating the PPAR- γ signalling pathway

In conclusion, PA2 inhibited TGF-β1-induced activation of HSCs by activating the PPAR-γ/Smad pathway. The findings suggested that PA2 may be an effective treatment for liver fibrosis.PMID:37615088 | DOI:10.1080/08916934.2023.2250101

Source: Autoimmunity - August 24, 2023 Category: Allergy & Immunology Authors: Yacong Xiao Xiujuan Li Li Wang Mingyue Hu Youlin Liu Source Type: research