Ex vivo dual gene therapy using human adipocytes secreting anti-HER2 antibody on HER2-positive xenograft tumor models

CONCLUSION: Ex vivo gene-transduced adipocytes might be useful for cell-based gene therapy. This system may be a platform for various antibody therapies.PMID:37612442 | DOI:10.1007/s12282-023-01497-8

Source: Breast Cancer - August 23, 2023 Category: Cancer & Oncology Authors: Ryotaro Teranaka Hiroshi Fujimoto Takahito Masuda Masayuki Kuroda Yasuyuki Aoyagi Takeshi Nagashima Mamoru Takada Junta Sakakibara Hideyuki Yamada Hiroto Yamamoto Yoshitaka Kubota Masayuki Ohtsuka Source Type: research