Design, QSAR methodology, synthesis and assessment of some structurally different xanthone derivatives as selective Cox-2 inhibitors for their anti-inflammatory properties

CONCLUSION: With the aim to evaluate the compounds for their anti-inflammatory activity, it was observed that the newly designed xanthonic compounds also possess a safe toxicity margin and hence can be utilized by the researchers to develop hybrid xanthonic moieties that can specifically target the enzyme COX-2.PMID:37594099 | DOI:10.2174/1573406419666230818092253

Source: Medicinal Chemistry - August 18, 2023 Category: Chemistry Authors: Riya Saikia Kalyani Pathak Aparoop Das Dubom Tayeng Mohammad Zaki Ahmed Jyotirmoy Das Smita Bordoloi Manash Pratim Pathak Source Type: research