Use of Stem Cells for the Treatment of Musculoskeletal Injuries in Horses

Mesenchymal stem cells (MSCs) are used as a regenerative therapy in horses for musculoskeletal injury since the late 1990s and in some regions are standard of care for certain injuries. Yet, there is no Food and Drug Administration –approved MSC therapeutic in the United States for horses. In humans, lack of regulatory approval in the United States has been caused by failure of late-phase clinical trials to demonstrate consistent efficacy, perhaps because of nonuniformity of MSC preparation and application techniques. This a rticle discusses clinical evidence for musculoskeletal applications of MSCs in the horse and current challenges to marketing approval.
Source: Veterinary Clinics of North America: Equine Practice - Category: Veterinary Research Authors: Source Type: research