Impact of stenosis resistance and coronary flow capacity on fractional flow reserve and instantaneous wave-free ratio discordance: a  combined analysis of DEFINE-FLOW and IDEAL

CONCLUSIONS: Discordance with FFR+/iFR- is characterised by maximal flow values, CFR, and CFC patterns similar to FFR-/iFR- concordance that justifies conservative therapy. Discordance with FFR-/iFR+ on the other hand, is characterised by low flow values, CFR, and CFC patterns similar to iFR+/FFR+ concordance that may benefit from percutaneous coronary intervention.PMID:37594612 | DOI:10.1007/s12471-023-01796-x

Source: Netherlands Heart Journal - August 18, 2023 Category: Cardiology Authors: Val érie Stegehuis Coen Boerhout Yuetsu Kikuta Maribel Cambero-Madera Niels van Royen Hitoshi Matsuo Masafumi Nakayama Guus de Waard Paul Knaapen Sukhjinder Nijjer Ricardo Petraco Maria Siebes Justin Davies Javier Escaned Tim van de Hoef Jan Piek Source Type: research