PAD4-Induced NETosis Via Cathepsin G-Mediated Platelet-Neutrophil Interaction in ChAdOx1 Vaccine-Induced Thrombosis

CONCLUSIONS: Patients with VITT display enhanced thrombogenesis by PAD4-mediated NETs formation via cathepsin G-mediated platelet/neutrophil interaction.PMID:37586040 | DOI:10.1161/ATVBAHA.123.319522

Source: Arteriosclerosis, Thrombosis and Vascular Biology - August 16, 2023 Category: Cardiology Authors: Roberto Carnevale Martina Leopizzi Marcello Dominici Giulia d'Amati Simona Bartimoccia Cristina Nocella Vittoria Cammisotto Alessandra D'Amico Valentina Castellani Francesco Baratta Alessia Bertelli Alessio Arrivi Danilo Toni Manuela De Michele Pasquale P Source Type: research