The onchocerciasis hypothesis of nodding syndrome
by Robert Colebunders, Amber Hadermann, Joseph Nelson Siewe Fodjo
Nodding syndrome (NS) is a phenotypic presentation of onchocerciasis-associated epilepsy (OAE). OAE is an important public health problem in areas with high ongoingOnchocerca volvulus transmission. OAE, including NS, is preventable by strengthening onchocerciasis elimination programs. The presence of tau in OAE postmortem brains could be the consequence of neuroinflammation directly or indirectly induced byO.volvulus. Omics research is needed to investigate whetherO.volvulus worms contain a neurotropic virus.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Robert Colebunders Source Type: research
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