Cancers, Vol. 15, Pages 4124: A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population

Conclusion: The previously validated PRS models have a similar observed accuracy in the Norwegian data as in the UK and Estonian populations. A PRS provides a meaningful association with the age of onset of BC and lifetime risk. Therefore, as suggested in Estonia, a PRS may also be integrated into the screening strategy for BC in Norway.

Source: Cancers - August 16, 2023 Category: Cancer & Oncology Authors: Bayram Cevdet Akdeniz Morten Mattingsdal Mev Dominguez-Valentin Oleksandr Frei Alexey Shadrin Mikk Puustusmaa Regina Saar Siim S õber P ål Møller Ole A. Andreassen Peeter Padrik Eivind Hovig Tags: Article Source Type: research