Novel object recognition test as an alternative approach to assessing the pharmacological profile of sigma-1 receptor ligands

CONCLUSIONS: The nonlinear dose-response effect of PRE-084 in this assay does not justify its use for routine assessment of the functional activity of σ1R ligands.PMID:37572216 | DOI:10.1007/s43440-023-00516-x

Source: Pharmacological Reports - August 12, 2023 Category: Drugs & Pharmacology Authors: Katarzyna Szczepa ńska Andrzej J Bojarski Piotr Popik Natalia Malikowska-Racia Source Type: research