Decoding the Possible Molecular Mechanisms in Pediatric Wilms Tumor and Rhabdoid Tumor of the Kidney through Machine Learning Approaches

Conclusion: The application of the machine learning methods could identify mRNA/miRNA patterns to discriminate WT from RT. The identified miRNAs/mRNAs panels could offer novel insights into the underlying molecular mechanisms that are responsible for the initiation and development of these cancers. They may provide further insight into the pathogenesis, prognosis, diagnosis, and molecular-targeted therapy in pediatric renal tumors.PMID:37548233 | DOI:10.1080/15513815.2023.2242979

Source: Fetal and Pediatric Pathology - August 7, 2023 Category: Pathology Authors: Seyed Mahdi Hosseiniyan Khatibi Yalda Rahbar Saadat Seyyedeh Mina Hejazian Simin Sharifi Mohammadreza Ardalan Mohammad Teshnehlab Sepideh Zununi Vahed Saeed Pirmoradi Source Type: research