Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts

ConclusionOur findings suggest that encapsulation of the virus in thiolated chitosan and CD44 targeting enhanced retention and sustained release of the virus in tumors as compared to pure NDV, with increased oncolytic effect both in vitro and in vivo.
Source: Cancer Nanotechnology - Category: Cancer & Oncology Source Type: research