Visualizing mast cell migration to tumor sites using sodium iodide symporter of nuclear medicine reporter gene

CONCLUSION: These findings suggest that the sodium iodide symporter can serve as a reliable nuclear medicine reporter gene for non-invasively imaging the biological activity of mast cells in mice with lung tumors. Visualizing mast cells in the tumor microenvironment via a nuclear medicine reporter gene would provide valuable insights into their biological functions.PMID:37562258 | DOI:10.1016/j.neo.2023.100925

Source: Neoplasia - August 10, 2023 Category: Cancer & Oncology Authors: Seul-Gi Oh Jun Young Choi Jae-Eon Lee SoYeon Jeon Bo-Ra Lee Kwang Hee Son Sang Bong Lee Beum-Soo An Dae Youn Hwang Seong-Jang Kim Ki-Tae Ha Jaetae Lee Yong Hyun Jeon Source Type: research