Medication adjustment of afatinib and combination therapy with sitagliptin for alleviating afatinib-induced diarrhea in rats

In conclusion, sitagliptin exhibits promising potential as a therapeutic option for managing afatinib-induced diarrhea. Taken together, our study provides valuable insights into alleviating afatinib-induced diarrhea through both afatinib medication adjustment and sitagliptin combination therapy.PMID:37567055 | DOI:10.1016/j.neo.2023.100922

Source: Neoplasia - August 11, 2023 Category: Cancer & Oncology Authors: Li Zhang Anna Hu Yan Wang Yuxin Yang Yalan Liu Lian Xu Lei Wang Zeneng Cheng Source Type: research