Differential effects on renal function and glucose metabolism of renal dependent bezafibrate and non-renal dependent pemafibrate in patients with hypertriglyceridemia

CONCLUSION: Our findings indicate that switching from bezafibrate to pemafibrate produces a significant decrease in serum creatinine and increases in eGFR and hemoglobin A1c in patients with hypertriglyceridemia, suggesting that the effects on renal function and glucose metabolism differ among fibrates.PMID:37548458 | DOI:10.5414/CP204408

Source: Clinical Pharmacology and Therapeutics - August 7, 2023 Category: Drugs & Pharmacology Authors: Mana Nishida Takeshi Horio Yusuke Fukuda Yuki Hayakawa Yu Tateishi Mayumi Akai Masanori Emoto Takamasa Hasegawa Masahito Imanishi Source Type: research