E-086 The effect of covid-19 vaccines on stroke outcomes: a single-center study

ConclusionAlthough vaccination did not show any significant difference in stroke patient outcomes on follow-up, vaccines were associated with lower rates of morbidity and mortality at discharge among stroke patients during the pandemic.Abstract E-086 Table 1Comparison of outcomes between COVID-19-positive unvaccinated vs. fully vaccinated patients presenting with stroke.*Adjusted for hypertension, atrial fibrillation, PVD, admission NIHSS, ASPECTS, tandem occlusion, and thrombectomy Unvaccinated Vaccinated Effect Variable Unadjusted Value (95% CI ) Unadjusted p-value Adjusted Value (95% CI )* Adjusted p-value* Primary Outcome mRS at discharge, median (IQR) 4 (2–5) 3 (1–4) Common Odds Ratio 0.508 (0.301–0.859) 0.011 0.490 (0.211–1.139) 0.098 Secondary Outcomes mRS 0–1 at discharge, n (%) 32/134 (23.9) 24/64 (37.5) Odds Ratio 1.913 (1.005-3.639) 0.048 1.733 (0.583–5.149) 0.322 mRS 0–2 at discharge, n (%) 41/134 (30.6) 29/64 (45.3) Odds Ratio 1.879 (1.017–3.473) 0.044 2.278 (0.757–6.858) 0.143 NIHSS at 24 hours, median (IQR) 6 (1–19) 3 (1–8) Beta -4.062 (-7.072– -1.053) 0.008 -1.919 (-4.362–0.524) 0.122 NIHSS at discharge, median (IQR) 6 (1–21) 2 (0–6) Beta -6.882 (-11.363– -2.401) 0.003 -3.589 (-8.490–1.312) 0.149 Mortality at discharge, n (%) 27/134 (20.2) 5/64 (7.8) Odds Ratio 0.336 (0.123–0.918) 0.033 0.556 (0.069–4.479) 0.581 mRS at 3 months, me...
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research