O-012 Relationship between clot composition and procedural results for ischemic stroke aspiration thrombectomy: subset analysis from the INSIGHT registry

ConclusionsClot removed during neuroendovascular procedures can differ in consistency and removability, leading to an increased focus on thrombus composition as a crucial variable for improving outcomes of ischemic stroke. In this study, good final revascularization (mTICI 2b-3 at the final angiogram) occurred after aspiration thrombectomy regardless of clot composition. Ongoing analysis of collected specimens is expected to provide valuable information regarding thrombus biology and etiology and to aid in diagnosis, prognosis, and drug development.Abstract O-012 Table 1Clot composition vs procedural results for ischemic stroke aspiration thrombectomy Ischemic stroke cohort (N=388) Firm red clot (N=165) Soft red clot (N=151) Firm white clot (N=37) Soft white clot (N=18) Percent of total,% 100% 42.5% 38.9% 9.5% 4.6% First pass performed with ADAPT (vs ADAPT plus stent retriever),% (n/N) 75.3% (292/388) 80.6% (133/165) 74.2% (112/151) 67.6% (25/37) 72.2% (13/18) Clot extracted with first pass,% (n/N) 54.9% (213/388) 50.9% (84/165) 58.9% (89/151) 64.9% (24/37) 44.4% (8/18) Total number of passes for the target lesion, mean (SD) 1.9 (1.3) 1.9 (1.1) 1.8 (1.3) 1.6 (0.9) 2.4 (1.5) mTICI 2b-3 after first pass,% (n/N) 71.1% (251/353) 69.7% (101/145) 71.5% (103/144) 78.1% (25/32) 58.8% (10/17) mTICI 2c-3 after first pass,% (n/N) 52.1% (184/353) 49.7% (72/145) 51.4% (74/144) 65.6% (21/32) 41.2% (7/17) mTICI 2b-3 at final angiogram,% (n/N) 97.9% (380/388) 97.0% (160/165) 98.0% (14...
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: SNIS 20th annual meeting oral abstracts Source Type: research