Bioinformatics-based design of a fusion vaccine with CTLA-4 variable region to combat Brucella

This study showed that the designed vaccine containing CTLA-4 had high potency against Brucella, which could provide a reference for the future development of efficient brucellosis vaccines.PMID:37493775 | PMC:PMC10361638 | DOI:10.1590/1414-431X2023e12938

Source: Braz J Med Biol Res - July 26, 2023 Category: Research Authors: W H Guo Y J Zhu G Haimiti X R Xie C Niu M Li J Shi Z W Yin M K Yu J B Ding F B Zhang Source Type: research