A Prochlorperazine-Induced Decrease in Autonomous Muscle Activity during Hindlimb Unloading Is Accompanied by Preserved Slow Myosin mRNA Expression

In this study, we found that prochlorperazine blocks slow-to-fast fiber-type transformation in disused skeletal muscles of rats, possibly through affecting calcium and ROS-related signaling.PMID:37504270 | DOI:10.3390/cimb45070354

Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Kristina A Sharlo Irina D Lvova Sergey A Tyganov Ksenia V Sergeeva Vitaly Y Kalashnikov Ekaterina P Kalashnikova Timur M Mirzoev Grigoriy R Kalamkarov Tatiana F Shevchenko Boris S Shenkman Source Type: research