Atypical endometriosis: a review of an incompletely understood putative precursor of endometriosis-associated ovarian carcinoma

Endometriosis is a common, morbid disease affecting 10% of reproductive age women. While typically considered a benign entity, approximately 1% of endometriotic foci will give rise to malignancy. Predicting which lesions have a higher risk of progression has been an area of recent interest, with a resurgence of the term “atypical endometriosis” (AE) in the literature. AE is defined as endometriosis with architectural and/or cytologic atypia. However, the inclusion of both architectural and cytologic abnormalities has historically been controversial.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Mini-symposium: gynaecological pathology Source Type: research