Ten years' experience in prenatal diagnosis of α-thalassemia in a municipal hospital and retrospective analysis of ultrasonic abnormalities

CONCLUSIONS: The extensive experience at our center shows that carrier screening, molecular diagnostics, genetic counseling, and prenatal diagnosis are effective measures to prevent Hb Bart's hydrops fetalis syndrome. The ultrasonographic abnormalities in fetuses with Hb Bart's hydrops are mainly caused by an increase in cardiac output, which leads to the body cavity effusion from various organs.PMID:37477864 | DOI:10.1007/s12185-023-03643-6

Source: International Journal of Hematology - July 21, 2023 Category: Hematology Authors: Haijun Li Jinhua Wang Degang Wang Yujie Gan Yi Xiong Source Type: research