Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania

Photography of the patient showing a huge palpable parathyroid tumour with infiltration of the overlying skin (A); Gross appearance of the resected tumour specimen (B). Key Clinical MessageRare cancer originating from parathyroid parenchymal cells. Preoperative diagnosis is often difficult. Presents with normal serum levels of calcium and parathyroid hormone. Treated by en bloc resection. Benefits of adjuvant therapy are unclear.AbstractParathyroid carcinoma is an uncommon endocrine tumor. Its typical presentation is that of primary hyperparathyroidism with elevated serum calcium and parathormone levels. Nonfunctioning carcinoma of the parathyroid gland with normal serum calcium levels is extremely rare. This paper describes a case of nonfunctioning parathyroid carcinoma and brief literature review thereof.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research