Molecular predictors for decitabine efficacy in meningiomas – a pilot study
ConclusionEarly effects of DCT in meningiomas are strongly related with DNMT1 expression, while clinical, histological, and molecular predictors for efficacy are sparse. Kinetics of drug efficacy might indicate necessity of repeated exposition and encourage further analyses.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research