miR ‐200a‐3p regulates epithelial–mesenchymal transition and inflammation in chronic rhinosinusitis with nasal polyps by targeting ZEB1 via ERK/p38 pathway

ConclusionsmiR-200a-3p suppresses EMT and inflammation by regulating the expression of ZEB1 via the ERK/p38 pathway. Our study presents new ideas for protecting nasal epithelial cells from tissue remodeling and finding a possible target for disease.

Source: International Forum of Allergy and Rhinology - July 20, 2023 Category: Allergy & Immunology Authors: Yisha Wu, Kaiyue Sun, Yanyi Tu, Ping Li, Dingqian Hao, Peng Yu, Aiping Chen, Yuzhu Wan, Li Shi Tags: ORIGINAL ARTICLE Source Type: research