Effect of Metformin on the Development of Age-related Macular Degeneration in the Diabetes Prevention Program Outcomes Study —Reply

In Reply We thank Asensio-S ánchez for sharing his thoughts and appreciate the opportunity to respond to the comments. Asensio-Sánchez has accurately interpreted that this is the first time in the Diabetes Prevention Program Outcomes Study that age-related macular degeneration (AMD) assessment was performed; therefore, one c annot hypothesize on the prevalence or stage of AMD before the images were acquired. The prevalence reported is for the current visit and does not account for previous time points. At the current visit, AMD was identified in 479 participants (30.0%) with early-stage AMD in 229 (14.4%), intermediate AMD in 218 (13.7%), and advanced AMD in 32 (2.0%). Breakdown by treatment arms is given in Figure 2.
Source: JAMA Ophthalmology - Category: Opthalmology Source Type: research