Metformin ameliorates liver fibrosis induced by congestive hepatopathy via the mTOR/HIF-1 α signaling pathway

CONCLUSIONS: Metformin inhibits CH-induced liver fibrosis. Functionally, this beneficial effect may be the result of inhibition of HSC activation and of the mTOR/HIF-1α signaling pathway.PMID:37451514 | DOI:10.1016/j.aohep.2023.101135

Source: Annals of Hepatology - July 14, 2023 Category: Gastroenterology Authors: Jing Yang Suxin Li Shengyan Liu Yuehui Zhang Dongqi Shen Peiju Wang Xiaowei Dang Source Type: research