Association of Molecular Profiles and Mutational Status With Distinct Histological Lung Adenocarcinoma Subtypes. An Analysis of the LACE-Bio Data

CONCLUSION: High TMB has a prognostic role in resectable lung ADC. The high TMB group had a poor outcome with AC, suggesting that this group may be better served with immune checkpoint therapy.PMID:37438216 | DOI:10.1016/j.cllc.2023.06.002

Source: Clinical Lung Cancer - July 12, 2023 Category: Cancer & Oncology Authors: Prashanth Ashok Kumar Maryam Karimi Alina Basnet Lesley Seymour Robert Kratzke Elizabeth Brambilla Thierry Le-Chevalier Jean-Charles Soria Ken Andr é Olaussen Siddhartha Devarakonda Ramaswamy Govindan Ming-Sound Tsao Frances A Shepherd Stefan Michiels St Source Type: research