Long-Term Environmental Exposures and Chronic Rhinosinusitis

In this issue of JAMA Otolaryngology –Head and Neck Surgery, Dr Yang and colleagues investigate the association of residential proximity to a commercial pesticide application site with the prevalence of chronic rhinosinusitis (CRS) in a retrospective cohort study. The study included 310 participants—90 patients with CRS and nasal p olyps (CRSwNP), 90 patients with CRS and without nasal polyps (CRSwoNP), and 130 control participants—who presented to a tertiary rhinology clinic in Los Angeles (California) from March 2018 to December 2022. Utilizing residential addresses, the authors determined pesticide exposure status based o n validated computational geographic information from the California Pesticide Use Report System. A patient was considered exposed to pesticide if there was a report of pesticide application within 2000 m of the patient’s residence in 2017.
Source: JAMA Otolaryngology - Head and Neck Surgery - Category: ENT & OMF Source Type: research