Variable Recovery of Cryopreserved Hematopoietic Stem Cells and Leukocyte Subpopulations in Leukapheresis Products

Due to the expansion of cell therapy using not only haematopoietic stem cells (HSC) but also other leukocyte subpopulations, the loss of these cells in cryopreserved apheresis products needs to be evaluated. Various factors that could negatively affect post-thaw recovery, such as leukapheresis product characteristics, storage time and cryopreservation protocols have been identified.
Source: Transfusion and Apheresis Science - Category: Hematology Authors: Source Type: research