Acid suppressants reduce the therapeutic effect of immune checkpoint inhibitors and increase the risk of acute kidney injury: a meta-analysis

ConclusionsIt was shown that ASs, especially PPIs, reduced ICI ’s therapeutic effect, while H2RAs had no effect, and ASs did not affect irAEs; however, it is a risk factor for ICIs-induced AKI.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research