Interferon lambda modulates proinflammatory cytokines production in PBMCs from patients with chronic kidney disease

CONCLUSION: High expression of IFNλ was found in CKD patients and was associated with eGFR and disease-related cytokines. More importantly, IFNλ promoted the expression of pro-inflammatory cytokines in PBMCs, suggesting a potential pro-inflammatory role of IFNλ in CKD.PMID:37394297 | DOI:10.1016/j.humimm.2023.06.001

Source: Human Immunology - July 2, 2023 Category: Allergy & Immunology Authors: Yuhao Xia Qiannan Yang Shang Ying Wu Zhicheng Wu Qian Li Jing Du Source Type: research