7TSG6 hyaluronan matrix remodeling dampens the inflammatory response during colitis

In conclusion, our data suggests that TSG6 exerts a tissue-protective, anti-inflammatory effect via the generation of HC:HA complexes that become dysregulated in IBD.PMID:37391162 | DOI:10.1016/j.matbio.2023.06.007

Source: Matrix Biology - June 30, 2023 Category: Molecular Biology Authors: Nansy Albtoush Kimberly A Queisser Ash Zawerton Mark E Lauer Ellen J Beswick Aaron C Petrey Source Type: research