Head-to-head comparison of plasma and PET imaging ATN markers in subjects with cognitive complaints

ConclusionPlasma p-tau181, as well as18F-florbetapir and18F-Florzolotau PET imaging can be considered as interchangeable biomarkers in the assessment of A β status in symptomatic stages of AD.18F-Florzolotau and18F-FDG PET imaging could serve as biomarkers for the severity of cognitive impairment. Our findings have implications for establishing a roadmap to identifying the most suitable ATN biomarkers for clinical use.
Source: Translational Neurodegeneration - Category: Neurology Source Type: research