KLF4 overexpression facilitates proliferation and represses apoptosis of granulosa cells in polycystic ovary syndrome

Conclusion KLF4 overexpression promoted RUNX2 expression by binding to the RUNX2 promoter, thereby further accelerating GC proliferation and repressing GC apoptosis in PCOS.

http://link.springer.com/10.1007/s13273-023-00354-1

Source: Molecular and Cellular Toxicology - June 27, 2023 Category: Cytology Source Type: research