Blood-borne extracellular vesicles of bacteria and intestinal cells in patients with psychotic disorders

CONCLUSIONS: Our results suggest that bactEV and host intestinal EV are decreased in patients with psychosis and that this topic is worthy of further investigation given potential pathophysiological implications. Possible mechanisms involve dysregulation of the gut microbiota by host EV, altered translocation of bactEV to systemic circulation where bactEV can interact with both the brain and the immune system.PMID:37354486 | DOI:10.1080/08039488.2023.2223572
Source: Nordic Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research