WIF1 was downregulated in cervical cancer due to promoter methylation

In conclusion, the methylation of the WIF1 promoter leads to the downregulation of WIF1 and the activation of Wnt/β-catenin signaling in cervical cancer cells. WIF1 is a tumor suppressor that is inactivated in cervical cancer.PMID:37306343 | DOI:10.18388/abp.2020_6700

Source: Acta Biochim Pol - June 12, 2023 Category: Biochemistry Authors: Ying Wang Shifa Yuan Jing Ma Hong Liu Lizhen Huang Fengzhen Zhang Xiaomei Wang Source Type: research