Determination of heavy metals and risk assessment in nail cosmetics sold in Seoul, Korea

The objective of this study was to evaluate some toxic levels of nail cosmetics marketed in Seoul, Korea and health risk assessment on human.METHODS: We collected 45 random nail cosmetics and analyzed for lead, cadmium, arsenic and antimony by inductively coupled plasma-optical emission spectrometry (ICP-OES).RESULTS: Four metals concentrations were Pb 0.037 ± 0.083 (<LOD ∼ 0.322) mg/kg, Cd 0.021 ± 0.058 (<LOD ∼0.342) mg/kg, As 0.094 ± 0.278 (<LOD ∼ 1.696) mg/kg and Sb 6.75 ± 17.54 (<LOD∼59.017) mg/kg respectively. The concentrations of antimony were significantly higher than other metal concentrations (p < 0.05) and Sb concentrations in 6 samples were above the acceptable limits in Korea. As the result of health risk assessment, MoS, HQ and HI values for Pb, As and Cd were within the permissible limit, but outside the acceptable range of Sb. LCR value was lower than the allowed limit for all nail cosmetics.Discussion and conclusion: 6 nail cosmetics had high antimony concentration which were higher than current legal limit in Korea. Because of 6 high antimony concentrations, MoS, HQ and HI was outside the acceptable range. LCR value for Pb, As and Cd was below 10-6 which was lower than the permissible limit and nail cosmetic may not possess lifetime cancer risk. Our results suggested that metals were present in nail cosmetics at diverse concentrations and some of nail cosmetics appeared to pose a harmful impact on health.PMID:37315294 | DOI:10.1080...
Source: Cutaneous and Ocular Toxicology - Category: Toxicology Authors: Source Type: research