Potential modifications of the PLASMIC scoring system for predicting thrombotic thrombocytopenic purpura: Sometimes, less is more

CONCLUSIONS: Based on the results of this validation study, removing MCV from the PLASMIC score led to the categorization of eight non-TTP cases in the low-risk category, and this could avoid unnecessary plasma exchange. However, in our study increasing the specificity was at the expense of the sensitivity by missing one patient with this new scoring system without MCV. Further multicenter studies with large sample sizes are required owing to the fact that different parameters may be effective in TTP prediction among different populations.PMID:37309683 | DOI:10.1111/ijlh.14115

Source: International Journal of Laboratory Hematology - June 13, 2023 Category: Hematology Authors: Bedrettin Orhan Vildan Özkocaman Çiğdem Akdemir Tuba Ersal İbrahim Ethem Pınar Cumali Yal çın Ömer Candar Sinem Çubukçu Tuba G üllü Koca P ınar Ambarcıoğlu R ıdvan Ali Fahir Özkalemkaş Source Type: research