S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos

Conclusion
Altogether, our results uncovered that S100A10 promotes HCC progression significantly via its transfer in EVs and regulating the protein cargoes of EVs. EV-S100A10 may be a potential therapeutic target and biomarker for HCC progression.

Source: Gut - June 7, 2023 Category: Gastroenterology Authors: Wang, X., Huang, H., Sze, K. M.-F., Wang, J., Tian, L., Lu, J., Tsui, Y.-M., Ma, H. T., Lee, E., Chen, A., Lee, J., Wang, Y., Yam, J. W. P., Cheung, T.-T., Guan, X., Ng, I. O.-L. Tags: Open access, Gut Hepatology Source Type: research